An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells

One of the driving forces of oncogenesis is tetraploidy, a duplication of the DNA content that, upon asymmetric cell division or progressive chromosome loss, can originate aneuploidy. Recent findings from our group indicate the existence of an immunosurveillance system that eliminates tetraploid can...

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Main Authors: Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Kepp, Oliver, Galluzzi, Lorenzo, Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583917/
https://ncbi.nlm.nih.gov/pubmed/23482968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22409
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