Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

We have identified a new Saccharomyces cerevisiae gene, MLH1 (mutL homolog), that encodes a predicted protein product with sequence similarity to DNA mismatch repair proteins of bacteria (MutL and HexB) and S. cerevisiae yeast (PMS1). Disruption of the MLH1 gene results in elevated spontaneous mutat...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Prolla, T A, Christie, D M, Liskay, R M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.407-415.1994
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