Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

We have identified a new Saccharomyces cerevisiae gene, MLH1 (mutL homolog), that encodes a predicted protein product with sequence similarity to DNA mismatch repair proteins of bacteria (MutL and HexB) and S. cerevisiae yeast (PMS1). Disruption of the MLH1 gene results in elevated spontaneous mutat...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Prolla, T A, Christie, D M, Liskay, R M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.407-415.1994
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