β-catenin Is Essential for Efficient In Vitro Premyogenic Mesoderm Formation but Can Be Partially Compensated by Retinoic Acid Signalling

Previous studies have shown that P19 cells expressing a dominant negative β-catenin mutant (β-cat/EnR) cannot undergo myogenic differentiation in the presence or absence of muscle-inducing levels of retinoic acid (RA). While RA could upregulate premyogenic mesoderm expression, including Pax3/7 and M...

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Autores principales: Wong, Jacob, Mehta, Virja, Voronova, Anastassia, Coutu, Josée, Ryan, Tammy, Shelton, Michael, Skerjanc, Ilona S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583846/
https://ncbi.nlm.nih.gov/pubmed/23460868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057501
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