MyoD Directly Up-regulates Premyogenic Mesoderm Factors during Induction of Skeletal Myogenesis in Stem Cells

Gain- and loss-of-function experiments have illustrated that the family of myogenic regulatory factors is necessary and sufficient for the formation of skeletal muscle. Furthermore, MyoD required cellular aggregation to induce myogenesis in P19 embryonal carcinoma stem cells. To determine the mechan...

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Autors principals: Gianakopoulos, Peter J., Mehta, Virja, Voronova, Anastassia, Cao, Yi, Yao, Zizhen, Coutu, Josée, Wang, Xiaonan, Waddington, Michelle S., Tapscott, Stephen J., Skerjanc, Ilona S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024746/
https://ncbi.nlm.nih.gov/pubmed/21078671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163709
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