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β-catenin Is Essential for Efficient In Vitro Premyogenic Mesoderm Formation but Can Be Partially Compensated by Retinoic Acid Signalling
Previous studies have shown that P19 cells expressing a dominant negative β-catenin mutant (β-cat/EnR) cannot undergo myogenic differentiation in the presence or absence of muscle-inducing levels of retinoic acid (RA). While RA could upregulate premyogenic mesoderm expression, including Pax3/7 and M...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583846/ https://ncbi.nlm.nih.gov/pubmed/23460868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057501 |
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