The transcription factor E2F-1 mediates the autoregulation of RB gene expression.
The retinoblastoma (RB) gene is the prototype tumor suppressor gene. Mutations in this gene are often associated with the occurrence of various tumors. Several mutations have been found in the promoter region of the gene, suggesting that inappropriate transcriptional regulation of the RB gene contri...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358379/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.299-309.1994 |
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