Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1 in the gastric epithelium

BACKGROUND: Aberrant methylation patterns in CpG island are known to be influential in gene silencing. Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor. We report an investigation into the effect of HRH2 promoter polymorphism (rs2607474 G...

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Main Authors: Nomura, Tomoe, Tahara, Tomomitsu, Shiroeda, Hisakazu, Minato, Takahiro, Matsue, Yasuhiro, Hayashi, Ranji, Matsunaga, Kazuhiro, Otsuka, Toshimi, Nakamura, Masakatsu, Toshikuni, Nobuyuki, Shibata, Tomoyuki, Arisawa, Tomiyasu
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583698/
https://ncbi.nlm.nih.gov/pubmed/23280118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-1
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