Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1 in the gastric epithelium

BACKGROUND: Aberrant methylation patterns in CpG island are known to be influential in gene silencing. Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor. We report an investigation into the effect of HRH2 promoter polymorphism (rs2607474 G...

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Bibliografische gegevens
Hoofdauteurs: Nomura, Tomoe, Tahara, Tomomitsu, Shiroeda, Hisakazu, Minato, Takahiro, Matsue, Yasuhiro, Hayashi, Ranji, Matsunaga, Kazuhiro, Otsuka, Toshimi, Nakamura, Masakatsu, Toshikuni, Nobuyuki, Shibata, Tomoyuki, Arisawa, Tomiyasu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583698/
https://ncbi.nlm.nih.gov/pubmed/23280118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-1
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