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The silence of MUC2 mRNA induced by promoter hypermethylation associated with HBV in Hepatocellular Carcinoma
BACKGROUND: To evaluate the promoter methylation status of MUC2 gene and mRNA expression in patients with hepatocellular carcinoma. METHODS: We analyzed MUC2 methylation by MSP, and MUC2 mRNA by real-time PCR in 74 HCC. RESULTS: MUC2 mRNA were lower in HCC tissues (Mean (-ΔCt) = −4.70) than that in...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583682/ https://ncbi.nlm.nih.gov/pubmed/23347460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-14 |
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