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The Silencing of RECK Gene is Associated with Promoter Hypermethylation and Poor Survival in Hepatocellular Carcinoma

Background: To evaluate the promoter methylation status of RECK gene and mRNA expression in patients with hepatocellular carcinoma (HCC). Methods: We analyzed RECK methylation by MSP, and RECK mRNA by real-time PCR in 74 HCC. The liver cell lines (7721, Chang and Hep-G2) were treated with 5-Aza-CdR...

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Hlavní autoři: Zhang, Changsong, Ling, Yang, Zhang, Chenghui, Xu, Yun, Gao, Lu, Li, Rong, Zhu, Jing, Fan, Lieying, Wei, Lixin
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303171/
https://ncbi.nlm.nih.gov/pubmed/22419890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4038
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