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Downregulation of Mcl-1 synergizes the apoptotic response to combined treatment with cisplatin and a novel fiber chimeric oncolytic adenovirus

The aim of this study was to examine the effects of SG511, a novel fiber chimeric oncolytic adenovirus with E1B 55-kDa deleted, combined with cisplatin on cancer cells and to identify their underlying mechanisms. The combined effect of SG511 and cisplatin on HeLa and HT-29 cells was assessed by a cr...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: YOU, LIANGSHUN, WANG, YING, JIN, YINGMING, QIAN, WENBIN
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: D.A. Spandidos 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583558/
https://ncbi.nlm.nih.gov/pubmed/22266706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1636
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