Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses

Pancreatic ductal adenocarcinoma (PDA) is characterized by its highly immunosuppressive tumor microenvironment (TME) that limits T cell infiltration and induces T cell hypofunction. Mesothelin-redirected chimeric antigen receptor T cell (meso-CAR T cell) therapy has shown some efficacy in clinical t...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Watanabe, Keisuke, Luo, Yanping, Da, Tong, Guedan, Sonia, Ruella, Marco, Scholler, John, Keith, Brian, Young, Regina M., Engels, Boris, Sorsa, Suvi, Siurala, Mikko, Havunen, Riikka, Tähtinen, Siri, Hemminki, Akseli, June, Carl H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928866/
https://ncbi.nlm.nih.gov/pubmed/29618658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99573
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller