High-Throughput Identification and Characterization of Novel, Species-selective GPR35 Agonists

Drugs targeting the orphan receptor GPR35 have potential therapeutic application in a number of disease areas, including inflammation, metabolic disorders, nociception, and cardiovascular disease. Currently available surrogate GPR35 agonists identified from pharmacologically relevant compound librar...

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Autores principales: Neetoo-Isseljee, Zaynab, MacKenzie, Amanda E., Southern, Craig, Jerman, Jeff, McIver, Edward G., Harries, Nicholas, Taylor, Debra L., Milligan, Graeme
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2013
Materias:
Cellular and Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583504/
https://ncbi.nlm.nih.gov/pubmed/23262279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201798
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