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Temporal Aspects of the Action of ASA404 (Vadimezan; DMXAA)

ASA404, a flavonoid tumor-vascular disrupting agent (Tumor-VDA), is in clinical trial for the treatment of non-small cell lung cancer. Its action differs from both that of the tubulin binding class of Tumor-VDAs and antiangiogenic agents. In mice, ASA404 induces a sequence of changes in tumor tissue...

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Hlavní autoři: Baguley, Bruce C, Siemann, Dietmar W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583340/
https://ncbi.nlm.nih.gov/pubmed/20964495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2010.529128
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