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The influence of the combined treatment with Vadimezan (ASA404) and taxol on the growth of U251 glioblastoma xenografts

BACKGROUND: One of the most important biological characteristics of Glioblastoma multiforme (GBM) is high vascular density. Vadimezan (ASA404, DMXAA) belongs to the class of small molecule vascular disrupting agents (VDA) that cause disruption of established tumor vessels and subsequent tumor hemorr...

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Detalhes bibliográficos
Main Authors: Milanović, Dušan, Braun, Friederike, Weber, Wolfgang, Grosu, Anca Ligia, Behe, Martin, Niedermann, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476988/
https://ncbi.nlm.nih.gov/pubmed/22695475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-242
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