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A cAMP and Ca(2+) coincidence detector in support of Ca(2+)-induced Ca(2+) release in mouse pancreatic β cells

The blood glucose-lowering hormone glucagon-like peptide-1 (GLP-1) stimulates cAMP production, promotes Ca(2+) influx, and mobilizes an intracellular source of Ca(2+) in pancreatic β cells. Here we provide evidence that these actions of GLP-1 are functionally related: they reflect a process of Ca(2+...

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Autors principals: Kang, Guoxin, Chepurny, Oleg G, Rindler, Michael J, Collis, Leon, Chepurny, Zina, Li, Wen-hong, Harbeck, Mark, Roe, Michael W, Holz, George G
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Ltd 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583090/
https://ncbi.nlm.nih.gov/pubmed/15860526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.087510
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