Effective treatment of rat adjuvant-induced arthritis by celastrol

We have previously reported an increase in interleukin (IL)-1β and IL-17 levels, and a continuous activation of caspase-1 in early rheumatoid arthritis (RA) patients. These results suggest that drugs targeting IL-1β regulatory pathways, in addition to tumor necrosis factor (TNF), may constitute prom...

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Bibliografske podrobnosti
Main Authors: Cascão, R., Vidal, B., Raquel, H., Neves-Costa, A., Figueiredo, N., Gupta, V., Fonseca, J.E., Moita, L.F.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582326/
https://ncbi.nlm.nih.gov/pubmed/22415021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2012.02.022
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