Potent Anti-Inflammatory and Antiproliferative Effects of Gambogic Acid in a Rat Model of Antigen-Induced Arthritis

Background. We have previously reported a continuous activation of caspase-1 and increased interleukin (IL)-1β levels in early rheumatoid arthritis (RA). These observations raised the hypothesis that drugs targeting the IL-1β pathway, in addition to tumour necrosis factor (TNF), may be particularly...

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Bibliografiske detaljer
Main Authors: Cascão, Rita, Vidal, Bruno, Raquel, Helena, Neves-Costa, Ana, Figueiredo, Nuno, Gupta, Vineet, Fonseca, João Eurico, Ferreira Moita, Luis
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929289/
https://ncbi.nlm.nih.gov/pubmed/24623960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/195327
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