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Comparative Modeling of the Human Monoamine Transporters: Similarities in Substrate Binding

[Image: see text] The amino acid compositions of the substrate binding pockets of the three human monoamine transporters are compared as is the orientation of the endogenous substrates, serotonin, dopamine, and norepinephrine, bound in these. Through a combination of homology modeling, induced fit d...

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Auteurs principaux: Koldsø, Heidi, Christiansen, Anja B., Sinning, Steffen, Schiøtt, Birgit
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2012
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582297/
https://ncbi.nlm.nih.gov/pubmed/23421681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300148r
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