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Comparative Modeling of the Human Monoamine Transporters: Similarities in Substrate Binding

[Image: see text] The amino acid compositions of the substrate binding pockets of the three human monoamine transporters are compared as is the orientation of the endogenous substrates, serotonin, dopamine, and norepinephrine, bound in these. Through a combination of homology modeling, induced fit d...

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Autori principali: Koldsø, Heidi, Christiansen, Anja B., Sinning, Steffen, Schiøtt, Birgit
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2012
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582297/
https://ncbi.nlm.nih.gov/pubmed/23421681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300148r
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