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Comparative Modeling of the Human Monoamine Transporters: Similarities in Substrate Binding

[Image: see text] The amino acid compositions of the substrate binding pockets of the three human monoamine transporters are compared as is the orientation of the endogenous substrates, serotonin, dopamine, and norepinephrine, bound in these. Through a combination of homology modeling, induced fit d...

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Autors principals: Koldsø, Heidi, Christiansen, Anja B., Sinning, Steffen, Schiøtt, Birgit
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2012
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582297/
https://ncbi.nlm.nih.gov/pubmed/23421681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300148r
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