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The sirtuin family’s role in aging and age-associated pathologies

The 7 mammalian sirtuin proteins compose a protective cavalry of enzymes that can be invoked by cells to aid in the defense against a vast array of stressors. The pathologies associated with aging, such as metabolic syndrome, neurodegeneration, and cancer, are either caused by or exacerbated by a li...

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Detalhes bibliográficos
Main Authors: Hall, Jessica A., Dominy, John E., Lee, Yoonjin, Puigserver, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582122/
https://ncbi.nlm.nih.gov/pubmed/23454760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64094
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