Coexistence of ribbon and helical fibrils originating from hIAPP(20–29) revealed by quantitative nanomechanical atomic force microscopy

Uncontrolled misfolding of proteins leading to the formation of amyloid deposits is associated with more than 40 types of diseases, such as neurodegenerative diseases and type-2 diabetes. These irreversible amyloid fibrils typically assemble in distinct stages. Transitions among the various intermed...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Shuai, Andreasen, Maria, Nielsen, Jakob T., Liu, Lei, Nielsen, Erik H., Song, Jie, Ji, Gang, Sun, Fei, Skrydstrup, Troels, Besenbacher, Flemming, Nielsen, Niels C., Otzen, Daniel E., Dong, Mingdong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581879/
https://ncbi.nlm.nih.gov/pubmed/23388629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209955110
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