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RNA-binding protein Sam68 controls synapse number and local β-actin mRNA metabolism in dendrites

Proper synaptic function requires the spatial and temporal compartmentalization of RNA metabolism via transacting RNA-binding proteins (RBPs). Loss of RBP activity leads to abnormal posttranscriptional regulation and results in diverse neurological disorders with underlying deficits in synaptic morp...

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Hlavní autoři: Klein, Matthew E., Younts, Thomas J., Castillo, Pablo E., Jordan, Bryen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581878/
https://ncbi.nlm.nih.gov/pubmed/23382180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209811110
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