Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation

Fibroblasts can be reprogrammed to induced pluripotent stem cells (iPSCs) by application of transcription factors octamer-binding protein 4 (Oct4), SRY-box containing gene 2 (Sox2), Kruppel-like factor 4 (Klf4), and c-Myelocytomatosis oncogene (c-Myc) (OSKM), but the underlying mechanisms remain unc...

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Bibliografiske detaljer
Main Authors: Wang, Guiying, Guo, Xudong, Hong, Wujun, Liu, Qidong, Wei, Tingyi, Lu, Chenqi, Gao, Longfei, Ye, Dan, Zhou, Yi, Chen, Jie, Wang, Jianmin, Wu, Minjuan, Liu, Houqi, Kang, Jiuhong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581874/
https://ncbi.nlm.nih.gov/pubmed/23386720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212769110
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