MicroRNA-200a Regulates Grb2 and Suppresses Differentiation of Mouse Embryonic Stem Cells into Endoderm and Mesoderm

The mechanisms by which microRNAs (miRNAs) affect cell fate decisions remain poorly understood. Herein, we report that miR-200a can suppress the differentiation of mouse embryonic stem (ES) cells into endoderm and mesoderm. Interestingly, miR-200a directly targets growth factor receptor-bound protei...

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Detalhes bibliográficos
Main Authors: Liu, Yang, Liu, Qidong, Jia, Wenwen, Chen, Jie, Wang, Jianmin, Ye, Dan, Guo, Xudong, Chen, Wen, Li, Guoping, Wang, Guiying, Deng, Anmei, Kang, Jiuhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715486/
https://ncbi.nlm.nih.gov/pubmed/23874841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068990
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