MicroRNA-200a Regulates Grb2 and Suppresses Differentiation of Mouse Embryonic Stem Cells into Endoderm and Mesoderm

The mechanisms by which microRNAs (miRNAs) affect cell fate decisions remain poorly understood. Herein, we report that miR-200a can suppress the differentiation of mouse embryonic stem (ES) cells into endoderm and mesoderm. Interestingly, miR-200a directly targets growth factor receptor-bound protei...

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Autores principales: Liu, Yang, Liu, Qidong, Jia, Wenwen, Chen, Jie, Wang, Jianmin, Ye, Dan, Guo, Xudong, Chen, Wen, Li, Guoping, Wang, Guiying, Deng, Anmei, Kang, Jiuhong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715486/
https://ncbi.nlm.nih.gov/pubmed/23874841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068990
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