microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming

Fibroblasts can be reprogrammed into induced pluripotent stem cells (iPSCs) by the application of Yamanaka factors (OSKM), but the mechanisms underlying this reprogramming remain poorly understood. Here, we report that Sox2 directly regulates endogenous microRNA-29b (miR-29b) expression during iPSC...

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Detalhes bibliográficos
Main Authors: Guo, Xudong, Liu, Qidong, Wang, Guiying, Zhu, Songcheng, Gao, Longfei, Hong, Wujun, Chen, Yafang, Wu, Minjuan, Liu, Houqi, Jiang, Cizhong, Kang, Jiuhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541656/
https://ncbi.nlm.nih.gov/pubmed/23266889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.180
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