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Amorphous Solid Dispersions of Sulfonamide/Soluplus® and Sulfonamide/PVP Prepared by Ball Milling

The aim of this paper is to investigate the physicochemical properties of binary amorphous dispersions of poorly soluble sulfonamide/polymeric excipient prepared by ball milling. The sulfonamides selected were sulfathiazole (STZ), sulfadimidine (SDM), sulfamerazine (SMZ) and sulfadiazine (SDZ). The...

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Bibliographische Detailangaben
Hauptverfasser: Caron, Vincent, Hu, Yun, Tajber, Lidia, Erxleben, Andrea, Corrigan, Owen I., McArdle, Patrick, Healy, Anne Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581644/
https://ncbi.nlm.nih.gov/pubmed/23389838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9931-7
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