Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN

Hsp27 (HSPB1) is usually overexpressed in breast cancers affecting the disease outcome and the sensitivity of tumors to chemotherapy and radiotherapy. Hsp27 interacts with other proteins such as β-catenin, histone deacetylase HDAC6, transcription factor STAT2 and procaspase-3. Phosphatase and tensin...

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Detalhes bibliográficos
Main Authors: Cayado-Gutiérrez, Niubys, Moncalero, Vera L., Rosales, Eliana M., Berón, Walter, Salvatierra, Edgardo E., Alvarez-Olmedo, Daiana, Radrizzani, Martín, Ciocca, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581620/
https://ncbi.nlm.nih.gov/pubmed/22907762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0367-x
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