Hsp27 (HSPB1): a possible surrogate molecular marker for loss of heterozygosity (LOH) of chromosome 1p in oligodendrogliomas but not in astrocytomas

In oligodendrogliomas, 1p loss of heterozygosity (LOH) is a predictor of good prognosis and treatment response. In contrast, in uveal melanomas, LOH of chromosome 3 has been linked to poor prognosis and downregulation of Hsp27. In the present study, we have analyzed the expression of heat-shock prot...

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Detalhes bibliográficos
Main Authors: Castro, Gisela N., Cayado-Gutiérrez, Niubys, Moncalero, Vera L., Lima, Patricia, De Angelis, Rodolfo Lucero, Chávez, Victor, Cuello-Carrión, F. Darío, Ciocca, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468673/
https://ncbi.nlm.nih.gov/pubmed/22806482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0350-6
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