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Molecular Dynamics Reveal Binding Mode of Glutathionylspermidine by Trypanothione Synthetase
The trypanothione synthetase (TryS) catalyses the two-step biosynthesis of trypanothione from spermidine and glutathione and is an attractive new drug target for the development of trypanocidal and antileishmanial drugs, especially since the structural information of TryS from Leishmania major has b...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581523/ https://ncbi.nlm.nih.gov/pubmed/23451087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056788 |
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