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Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
Most organisms use glutathione to regulate intracellular thiol redox balance and protect against oxidative stress; protozoa, however, utilize trypanothione for this purpose. Trypanothione biosynthesis requires ATP-dependent conjugation of glutathione (GSH) to the two terminal amino groups of spermid...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698887/ https://ncbi.nlm.nih.gov/pubmed/17124497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601440 |
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