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Lamin A/C Haploinsufficiency Modulates the Differentiation Potential of Mouse Embryonic Stem Cells

BACKGROUND: Lamins are structural proteins that are the major determinants of nuclear architecture and play important roles in various nuclear functions including gene regulation and cell differentiation. Mutations in the human lamin A gene cause a spectrum of genetic diseases that affect specific t...

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Detalhes bibliográficos
Main Authors: Sehgal, Poonam, Chaturvedi, Pankaj, Kumaran, R. Ileng, Kumar, Satish, Parnaik, Veena K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581495/
https://ncbi.nlm.nih.gov/pubmed/23451281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057891
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