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Stimulation of Bone Formation in Cortical Bone of Mice Treated with a Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity

To date, parathyroid hormone is the only clinically available bone anabolic drug. The major difficulty in the development of such drugs is the lack of clarification of the mechanisms regulating osteoblast differentiation and bone formation. Here, we report a peptide (W9) known to abrogate osteoclast...

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Main Authors: Furuya, Yuriko, Inagaki, Atsushi, Khan, Masud, Mori, Kaoru, Penninger, Josef M., Nakamura, Midori, Udagawa, Nobuyuki, Aoki, Kazuhiro, Ohya, Keiichi, Uchida, Kohji, Yasuda, Hisataka
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581422/
https://ncbi.nlm.nih.gov/pubmed/23319583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426080
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