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Stimulation of Bone Formation in Cortical Bone of Mice Treated with a Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity

To date, parathyroid hormone is the only clinically available bone anabolic drug. The major difficulty in the development of such drugs is the lack of clarification of the mechanisms regulating osteoblast differentiation and bone formation. Here, we report a peptide (W9) known to abrogate osteoclast...

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Autori principali: Furuya, Yuriko, Inagaki, Atsushi, Khan, Masud, Mori, Kaoru, Penninger, Josef M., Nakamura, Midori, Udagawa, Nobuyuki, Aoki, Kazuhiro, Ohya, Keiichi, Uchida, Kohji, Yasuda, Hisataka
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581422/
https://ncbi.nlm.nih.gov/pubmed/23319583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426080
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