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The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H(+)-ATPase (V-ATPase) and Cytohesin-2
Previously, we reported an acidification-dependent interaction of the endosomal vacuolar H(+)-ATPase (V-ATPase) with cytohesin-2, a GDP/GTP exchange factor (GEF), suggesting that it functions as a pH-sensing receptor. Here, we have studied the molecular mechanism of signaling between the V-ATPase, c...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581410/ https://ncbi.nlm.nih.gov/pubmed/23288846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409169 |
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