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The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H(+)-ATPase (V-ATPase) and Cytohesin-2

Previously, we reported an acidification-dependent interaction of the endosomal vacuolar H(+)-ATPase (V-ATPase) with cytohesin-2, a GDP/GTP exchange factor (GEF), suggesting that it functions as a pH-sensing receptor. Here, we have studied the molecular mechanism of signaling between the V-ATPase, c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hosokawa, Hiroyuki, Dip, Phat Vinh, Merkulova, Maria, Bakulina, Anastasia, Zhuang, Zhenjie, Khatri, Ashok, Jian, Xiaoying, Keating, Shawn M., Bueler, Stephanie A., Rubinstein, John L., Randazzo, Paul A., Ausiello, Dennis A., Grüber, Gerhard, Marshansky, Vladimir
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581410/
https://ncbi.nlm.nih.gov/pubmed/23288846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409169
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