The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H(+)-ATPase (V-ATPase) and Cytohesin-2

Previously, we reported an acidification-dependent interaction of the endosomal vacuolar H(+)-ATPase (V-ATPase) with cytohesin-2, a GDP/GTP exchange factor (GEF), suggesting that it functions as a pH-sensing receptor. Here, we have studied the molecular mechanism of signaling between the V-ATPase, c...

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Bibliografske podrobnosti
Main Authors: Hosokawa, Hiroyuki, Dip, Phat Vinh, Merkulova, Maria, Bakulina, Anastasia, Zhuang, Zhenjie, Khatri, Ashok, Jian, Xiaoying, Keating, Shawn M., Bueler, Stephanie A., Rubinstein, John L., Randazzo, Paul A., Ausiello, Dennis A., Grüber, Gerhard, Marshansky, Vladimir
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Bioenergetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581410/
https://ncbi.nlm.nih.gov/pubmed/23288846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409169
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