Interplay between Calmodulin and Phosphatidylinositol 4,5-Bisphosphate in Ca(2+)-induced Inactivation of Transient Receptor Potential Vanilloid 6 Channels

The epithelial Ca(2+) channel transient receptor potential vanilloid 6 (TRPV6) undergoes Ca(2+)-induced inactivation that protects the cell from toxic Ca(2+) overload and may also limit intestinal Ca(2+) transport. To dissect the roles of individual signaling pathways in this phenomenon, we studied...

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Bibliographic Details
Main Authors: Cao, Chike, Zakharian, Eleonora, Borbiro, Istvan, Rohacs, Tibor
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581402/
https://ncbi.nlm.nih.gov/pubmed/23300090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409482
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