Derivation of Human Induced Pluripotent Stem Cells from Patients with Maturity Onset Diabetes of the Young

Maturity onset diabetes of the young (MODY) is an autosomal dominant disease. Despite extensive research, the mechanism by which a mutant MODY gene results in monogenic diabetes is not yet clear due to the inaccessibility of patient samples. Induced pluripotency and directed differentiation toward t...

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Main Authors: Teo, Adrian K. K., Windmueller, Rebecca, Johansson, Bente B., Dirice, Ercument, Njolstad, Pal R., Tjora, Erling, Raeder, Helge, Kulkarni, Rohit N.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581399/
https://ncbi.nlm.nih.gov/pubmed/23306198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.428979
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