Haploinsufficiency of the Ammonia Transporter Rhcg Predisposes to Chronic Acidosis: Rhcg IS CRITICAL FOR APICAL AND BASOLATERAL AMMONIA TRANSPORT IN THE MOUSE COLLECTING DUCT

Ammonia secretion by the collecting duct (CD) is critical for acid-base homeostasis and, when defective, causes distal renal tubular acidosis (dRTA). The Rhesus protein RhCG mediates NH(3) transport as evident from cell-free and cellular models as well as from Rhcg-null mice. Here, we investigated i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Bourgeois, Soline, Bounoure, Lisa, Christensen, Erik I., Ramakrishnan, Suresh K., Houillier, Pascal, Devuyst, Olivier, Wagner, Carsten A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581388/
https://ncbi.nlm.nih.gov/pubmed/23281477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441782
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars