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The ammonia transporter RhCG regulates urinary acidification by interacting with vacuolar H(+)-ATPases in renal intercalated cells
Ammonium, stemming from renal ammoniagenesis, is a major urinary proton buffer and is excreted along the collecting duct. This process depends on the concomitant secretion of ammonia (NH(3)) by the NH(3) channel RhCG and of protons (H(+)) by the vacuolar-type H(+)-ATPase pump. Thus, urinary ammonium...
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| Publicado no: | Kidney Int |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166241/ https://ncbi.nlm.nih.gov/pubmed/29054531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.07.027 |
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