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Selective Serotonin Reuptake Inhibitors (SSRIs) Inhibit Insulin Secretion and Action in Pancreatic β Cells

Selective serotonin reuptake inhibitors (SSRIs) are antidepressants used for the treatment of mood and anxiety disorders. Here, we demonstrate that incubation (2 h) of murine islets or Min6 β cell line with the SSRIs paroxetine, fluoxetine, or sertraline inhibited insulin-induced Tyr phosphorylation...

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書誌詳細
主要な著者: Isaac, Roi, Boura-Halfon, Sigalit, Gurevitch, Diana, Shainskaya, Alla, Levkovitz, Yechiel, Zick, Yehiel
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581374/
https://ncbi.nlm.nih.gov/pubmed/23275337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.408641
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