Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance.

Samankaltaisia teoksia

• Serine Phosphorylation Proximal to Its Phosphotyrosine Binding Domain Inhibits Insulin Receptor Substrate 1 Function and Promotes Insulin Resistance
  Tekijä: Liu, Yan-Fang, et al.
  Julkaistu: (2004)
• Insulin stimulates PKCζ -mediated phosphorylation of insulin receptor substrate-1 (IRS-1): A self-attenuated mechanism to negatively regulate the function of IRS proteins.
  Tekijä: Liu, Yan-Fang, et al.
  Julkaistu: (2018)
• A Novel Domain Mediates Insulin-Induced Proteasomal Degradation of Insulin Receptor Substrate 1 (IRS-1)
  Tekijä: Boura-Halfon, Sigalit, et al.
  Julkaistu: (2010)
• Elimination of Negative Feedback Control Mechanisms Along the Insulin Signaling Pathway Improves β-Cell Function Under Stress
  Tekijä: Gurevitch, Diana, et al.
  Julkaistu: (2010)
• Selective Serotonin Reuptake Inhibitors (SSRIs) Inhibit Insulin Secretion and Action in Pancreatic β Cells
  Tekijä: Isaac, Roi, et al.
  Julkaistu: (2013)