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Effects of Cysteine Proteases on the Structural and Mechanical Properties of Collagen Fibers

Excessive cathepsin K (catK)-mediated turnover of fibrillar type I and II collagens in bone and cartilage leads to osteoporosis and osteoarthritis. However, little is known about how catK degrades compact collagen macromolecules. The present study is aimed to explore the structural and mechanical co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Panwar, Preety, Du, Xin, Sharma, Vidhu, Lamour, Guillaume, Castro, Mickael, Li, Hongbin, Brömme, Dieter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581366/
https://ncbi.nlm.nih.gov/pubmed/23297404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419689
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