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Two discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice
Previously we showed that transgenic mice expressing human HLA-DR3 gene are susceptible to PLP(91-110) induced experimental autoimmune encephalomyelitis (EAE) and can serve as an animal model of multiple sclerosis (MS). HLA-DR3 mice with EAE showed increased number of CD8 T cells indicating their im...
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主要な著者: | , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581307/ https://ncbi.nlm.nih.gov/pubmed/22459490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.02.004 |
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