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HLA-DQ8 (DQB1*0302) Restricted Th17 cells Exacerbate Experimental Autoimmune Encephalomyelitis in HLA-DR3 Transgenic Mice

Among all the genetic factors associated with MS susceptibility, MHC class II molecules have the strongest association. Although a direct role of DR alleles in MS have been confirmed, it has been difficult to understand the role of DQ alleles in disease pathogenesis, due to strong linkage disequilib...

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Detalhes bibliográficos
Main Authors: Mangalam, Ashutosh, Luckey, David, Basal, Eati, Jackson, Megan, Smart, Michelle, Rodriguez, Moses, David, Chella
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665933/
https://ncbi.nlm.nih.gov/pubmed/19342694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803918
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