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HLA-DQ8 (DQB1*0302) Restricted Th17 cells Exacerbate Experimental Autoimmune Encephalomyelitis in HLA-DR3 Transgenic Mice
Among all the genetic factors associated with MS susceptibility, MHC class II molecules have the strongest association. Although a direct role of DR alleles in MS have been confirmed, it has been difficult to understand the role of DQ alleles in disease pathogenesis, due to strong linkage disequilib...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665933/ https://ncbi.nlm.nih.gov/pubmed/19342694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803918 |
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