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Nucleic acid amplification in vitro: detection of sequences with low copy numbers and application to diagnosis of human immunodeficiency virus type 1 infection.

The enzymatic amplification of specific nucleic acid sequences in vitro has revolutionized the use of nucleic acid hybridization assays for viral detection. With this method, the copy number of a pathogen-specific sequence is increased several orders of magnitude before detection is attempted. The s...

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Bibliografski detalji
Glavni autori: Guatelli, J C, Gingeras, T R, Richman, D D
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC358112/
https://ncbi.nlm.nih.gov/pubmed/2650862
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