Enhanced Production of Acarbose and Concurrently Reduced Formation of Impurity C by Addition of Validamine in Fermentation of Actinoplanes utahensis ZJB-08196

Commercial production of acarbose is exclusively via done microbial fermentation with strains from the genera of Actinoplanes. The addition of C(7)N-aminocyclitols for enhanced production of acarbose and concurrently reduced formation of impurity C by cultivation of A. utahensis ZJB-08196 in 500-mL...

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Autors principals: Xue, Ya-Ping, Qin, Jun-Wei, Wang, Ya-Jun, Wang, Yuan-Shan, Zheng, Yu-Guo
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581085/
https://ncbi.nlm.nih.gov/pubmed/23484146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/705418
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