Newly Discovered Penicillin Acylase Activity of Aculeacin A Acylase from Actinoplanes utahensis

Aculeacin A acylase from Actinoplanes utahensis produced by Streptomyces lividans revealed acylase activities that are able to hydrolyze penicillin V and several natural aliphatic penicillins. Penicillin K was the best substrate, showing a catalytic efficiency of 34.79 mM(−1) s(−1). Furthermore, acu...

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Main Authors: Torres-Bacete, Jesús, Hormigo, Daniel, Stuart, Maribel, Arroyo, Miguel, Torres, Pedro, Castillón, María P., Acebal, Carmen, García, José L., de la Mata, Isabel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Enzymology and Protein Engineering
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950969/
https://ncbi.nlm.nih.gov/pubmed/17586674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00452-07
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