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Engineering the Substrate Specificity of a Thermophilic Penicillin Acylase from Thermus thermophilus

A homologue of the Escherichia coli penicillin acylase is encoded in the genomes of several thermophiles, including in different Thermus thermophilus strains. Although the natural substrate of this enzyme is not known, this acylase shows a marked preference for penicillin K over penicillin G. Three-...

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Bibliografische gegevens
Hoofdauteurs: Torres, Leticia L., Cantero, Ángel, del Valle, Mercedes, Marina, Anabel, López-Gallego, Fernando, Guisán, José M., Berenguer, José, Hidalgo, Aurelio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591942/
https://ncbi.nlm.nih.gov/pubmed/23263966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03215-12
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